Paget's Disease Treatment
Specialist assessment, monitoring and treatment of Paget's disease of bone, helping manage symptoms, monitor disease activity and reduce the risk of long-term complications.
Paget's disease is a disorder of bone remodelling that can affect different parts of the skeleton. Some patients require treatment while others benefit from monitoring and specialist follow-up.
What is Paget's disease of bone?
Paget's disease is a condition that affects the normal process of bone renewal. Bone is broken down and rebuilt more rapidly than usual, leading to areas of enlarged, weakened or structurally abnormal bone.
A disorder of bone remodelling
The condition most commonly affects the pelvis, spine, skull, femur and tibia. Some patients experience symptoms while others are diagnosed following routine blood tests or imaging.
Individualised management
Treatment decisions depend on disease activity, symptoms, affected bones, blood test results and the risk of future complications.
When specialist review may be useful
Not every patient with Paget's disease requires immediate treatment, but specialist review helps determine whether intervention or monitoring is most appropriate.
Common reasons for referral
- New diagnosis of Paget's disease
- Bone pain or discomfort
- Raised alkaline phosphatase levels
- Abnormal bone scans or X-rays
- Monitoring of established disease
Potential concerns
- Progressive disease activity
- Risk of deformity
- Joint problems near affected bone
- Fracture risk in some cases
- Need for specialist treatment planning
What the consultation may include
The aim is to understand the extent of disease activity, determine whether treatment is appropriate and develop a long-term monitoring plan.
Symptoms, previous investigations and family history are discussed.
Markers of bone turnover and disease activity are reviewed.
X-rays, bone scans and other investigations are assessed.
A personalised management strategy is developed.
How Paget's disease may be managed
Treatment depends on disease activity, symptoms and the bones involved. Some patients require medication while others benefit from observation and regular monitoring.
Medical treatment
- Bisphosphonate therapy where appropriate
- Monitoring of treatment response
- Assessment of disease activity
- Management of symptoms
- Review of associated bone health concerns
Long-term follow-up
- Regular blood test monitoring
- Imaging review where required
- Assessment of progression
- Monitoring for complications
- Ongoing specialist advice
Paget's disease treatment questions
Common questions about Paget's disease diagnosis, treatment and monitoring.
Does Paget's disease always require treatment?
No. Some patients are monitored without treatment, particularly if the disease is inactive and causing no symptoms.
Can Paget's disease cause pain?
Yes. Some patients experience bone pain, joint symptoms or discomfort related to affected areas of the skeleton.
How is disease activity monitored?
Blood tests, imaging and clinical review are commonly used to assess disease activity and treatment response.
Is Paget's disease cancer?
No. Paget's disease is a benign bone disorder, although specialist assessment helps monitor for complications and ensure appropriate management.
Book a Paget's disease consultation
If you have Paget's disease of bone or have been referred following abnormal blood tests or imaging, please contact the office to arrange a specialist consultation.
Contact details
For private appointments and general enquiries, please contact Professor Keen's office.